Pharmacology of the Neuromuscular Blockers
So you've been learning about NMBs and they've been throwing around all these unfamiliar terms, and you're like, "What the heck does that actually mean?" What does it mean if a NMB has an "intermediate duration" when time is relative? And is histamine release really THAT bad?
UNDER CONSTRUCTION
Also "biliary excretion" basically means that you eventually poop the drug out.
Renal excretion means you pee it out.
Hey, you gotta get rid of waste somehow.
Biliary excretion
Before I begin talking about biliary excretion, I would like to take a moment to show you this beautiful first line of the wikipedia page on bile:
UNDER CONSTRUCTION
Also "biliary excretion" basically means that you eventually poop the drug out.
Renal excretion means you pee it out.
Hey, you gotta get rid of waste somehow.
Biliary excretion
Before I begin talking about biliary excretion, I would like to take a moment to show you this beautiful first line of the wikipedia page on bile:
Note the 6th and 7th words of that sentence.
YES, THAT MEANS SOMEBODY, AT SOME POINT, ATE IT.
At some point in history, somebody out there thought, "Hmmm, I wonder what pure bile tastes like."
And then he or she went ahead and actually tried it.
Have you even thrown up and it was a nice green color? Or pooped and your poop was green. Ever wonder what makes it green? That's bile. And some of the neuromuscular blocking agents get to exit your body mixed in with it. I almost feel bad for them.
At some point in history, somebody out there thought, "Hmmm, I wonder what pure bile tastes like."
And then he or she went ahead and actually tried it.
Have you even thrown up and it was a nice green color? Or pooped and your poop was green. Ever wonder what makes it green? That's bile. And some of the neuromuscular blocking agents get to exit your body mixed in with it. I almost feel bad for them.